Proarrhythmic effects of antiarrhythmic drugs assessed by electrophysiologic study in recurrent sustained ventricular tachycardia.
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چکیده
منابع مشابه
Recurrent sustained ventricular tachycardia 3. Role of the electrophysiologic study in selection of antiarrhythmic regimens.
Twenty patients with recurrent sustained ventricular tachycardia (VT) underwent serial electrophysiological studies (EPS) 1) to determine the predictive value of the EPS in the selection of antiarrhythmic therapy, and 2) to establish the therapeutic efficacy of available antiarrhythmic agents. In each patient VT could be reproducibly initiated by programmed stimulation. After control EPS, the e...
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The proarrhythmic effects of class IA antiarrhythmic drugs were prospectively evaluated during programmed ventricular stimulation in 24 consecutive patients with frequent ventricular premature beats whose baseline study, performed while no antiarrhythmic drugs were being taken, showed no inducible sustained ventricular arrhythmias. No patient had nonsustained (greater than 5 beats) or sustained...
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18. El-Sherif N, Scherlag BJ, Lazzara R, Hope RR: Re-entrant arrhythmias in the later myocardial period. I. Conduction characteristics in the infarct zone. Circulation 55: 686, 1977 19. El-Sherif N, Hope RR, Scherlag BJ, Lazzara R: Re-entrant arrhythmias in the late myocardial infarction period. II. Patterns of initiation and termination. Circulation 55: 702, 1977 20. Spear JF, Horowitz LN, Moo...
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was effective for controlling 64% of patients, with partial control achieved in an additional 13%. The incidence of side effects necessitating drug withdrawal was 15%. In the study of Hammill et al, most patients (60%) had no significant cardiovascular disease, while 74% of Kerr’s group had primary AF without associated heart disease. We had a lower success rate than these 2 previous groups, bu...
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This study assessed the antiarrhythmic activity of amiloride in 35 patients with inducible sustained ventricular tachycardia. Patients had failed to respond to 3.6±1.0 antiarrhythmic drugs. Ventricular tachycardia was reproducibly induced by programmed electrical stimulation in all patients at the baseline study. Amiloride was given at 10 and 20 mg/day p.o. on a twice-daily schedule that achiev...
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ژورنال
عنوان ژورنال: Japanese Circulation Journal
سال: 1991
ISSN: 0047-1828,1347-4839
DOI: 10.1253/jcj.55.133